Ctrl as primary modifier. Tab management, address bar, history, bookmarks, and DevTools all use Ctrl. This matches Chrome on Windows, so if you're switching from Chrome to Edge, the core shortcut set is familiar.
F-key shortcuts. F-keys work without Fn on Windows. F12 opens DevTools directly. F5 reloads the page. Alt+D or F6 focuses the address bar, both work in Edge on Windows.
Edge-specific features on Windows. Collections (saving and organizing web content), the Copilot and sidebar panel, Immersive Reader, vertical tabs, and web capture each have dedicated shortcuts on Windows. These are the areas where Edge's shortcut reference differs from Chrome's.
Windows 11 integration. A small number of Edge shortcuts interact with Windows 11 system features. These are covered in the table above where applicable.
DevTools. F12 or the Ctrl-based shortcut opens DevTools. Edge DevTools are built on the same infrastructure as Chrome DevTools, so the panel navigation and in-DevTools shortcut set is familiar to anyone who has used Chrome's tools.